Association of Hydroxychloroquine use and Hemolytic Anemia in Patients With Low Levels of Glucose-6-Phosphate Dehydrogenase

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Background: Glucose-6-phosphate dehydrogenase deficiency (G6PD) is linked to hemolytic anemia with certain medications and is the most common enzyme deficiency worldwide. Although the American College of Rheumatology does not recommend routine testing for G6PD prior to initiation of hydroxychloroquine (HCQ), the package insert for HCQ does recommend careful use in patients with G6PD deficiency.

Methods: We identified eligible subjects seen at our tertiary care, urban medical center between 1997 and 2018. Case records were analyzed for G6PD deficiency, HCQ use, length of exposure to HCQ, demographic characteristics, and laboratory evidence of hemolysis.

Results: We found 5264 patients who were prescribed HCQ, of which 49.5% (2605 patients) were screened for G6PD deficiency. Of the screened patients, 36 were found to be G6PD-deficient. Of the G6PD-deficient patients, 18 were exposed to HCQ. No evidence of hemolysis was found in these exposed patients.

Conclusions: Despite more than 500 months of cumulative exposure time to HCQ, there were no cases of hemolysis. These findings are in line with recently published data and suggest that this interaction is not associated with clinically significant hemolysis in our population of mainly African American and Hispanic patients. Limitations to our study are potential bias due to case review design and lack of prior assessment of episodes of hemolysis before HCQ exposure. A high proportion of our patients were Hispanic, suggesting no increase of adverse events in this subgroup. A larger longitudinal trial would be needed to definitively answer the question of the safety of HCQ in G6PD-deficient patients

G6PD and hydroxychloroquine in the COVID19 era: a mini review

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The coronavirus disease 2019 (COVID-19) is until today a global health emergency. In an immense efort, efective drugs against COVID-19 are searched and intensive researches on possible repurposing of antiviral agents are performed. Since chloroquine (CQ) and hydroxychloroquine (HCQ) have shown in vitro anti- COVID-19 activities, the potential efect of CQ/ HCQ to treat and/or prevent COVID-19 infection has caused global attention.

Risk of Asymptomatic Spread Minimal. Variants Over-Hyped. Masks Pointless. An Interview With Professor Jay Bhattacharya

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New variants are of no concern. There is no need to cancel summer holidays. Millions vaccinated, coupled with immunity from millions of prior infections means we can surf on the crest of the third wave, rather than being remotely concerned about it. In fact, the UK should open now. And vaccine passports, certificates, or whatever name they are being given, will do nothing to improve the health of the population – all headlines we have read and heard over the past week or so.

Data substantiating wide asymptomatic spread of COVID-19 remains elusive

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Fear of symptom-free transmission was a major driver of the highly restrictive mitigation measures imposed over the past year.

ard data on the true prevalence of asymptomatic COVID-19 spread remains elusive, with scientists struggling to quantify just how often carriers of the SARS-Cov-2 virus transmit it without outward signs of illness. 

The Truth about Virus Isolation - Dr Sam Bailey

 

https://odysee.com/@januszkowalskii1979:e/The-Truth-about-Virus-Isolation---Dr-Sam-Bailey:1

The Truth about Virus Isolation. What does it really mean to isolate a virus?

approx 14 min.

#virusisolation #virusisolate

BREAKING NEWS FROM People’s Union of Britain

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We have just received confirmation that the case files in the P.U.B. prosecution of the four horsemen of the Covid Apocalypse, are with the court’s listing department, who expect a hearing will soon be listed, following checks by the legal team at Bromley Magistrates, to which it was transferred for processing and listing by the Westminster court.

Being moved to the court which deals with all PCPs (Private Criminal Prosecutions), it is anticipated the fireworks will start going off very soon.

From the very start of this extraordinary case, it was always known to have taken a goodly time in getting to its present position. The major fraud case against both the mortgage and banksters took nearly 10 years to get this far, so looking at 10 months down the line we know, not only the case is rock solid but als that there are a huge swathe of the legal system behind us and making swift passage for the case of the centuries. This will be the single biggest legal case in the history of the British Isles.

There are many side cases going on yet this one in the High Court, probably the Old Bailey, the Common Law court of the Land due to a jury of 12 good men and women true, will be the show stopper of all showstoppers. The brilliant point is that its huge impact will force by every rule book the BBC, ITV, SKY and others to report truth for the first time in decades. It will destroy the curtain they have used to cover up so much criminality.

Military Unveils Next Stage of COVID Vaccines on 60 Minutes: Implantable Microchips

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"Retired Colonel Matt Hepburn, an army infectious disease physician heading up DARPA’s response to the pandemic, appeared on 60 Minutes to demonstrate the technology.

Holding up a vial of green tissue-like gel, which contains the chip, Hepburn proclaimed:

You put it underneath your skin and what that tells you is that there are chemical reactions going on inside the body, and that signal means you are going to have symptoms tomorrow.”

Sensational verdict from Weimar: no masks, no distance, no more tests for students

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"On April 8, 2021, the Weimar Family Court ruled in summary proceedings (Ref.: 9 F 148/21) that two Weimar schools are prohibited, effective immediately, from requiring students to wear any type of mouth-nose covering (especially qualified masks such as FFP2 masks), to comply with AHA minimum distances, and/or to participate in SARS-CoV-2 rapid testing."

Why is it so important for everyone to be vaccinated?

This video shows what the vaccine does to us humans, among other things, and what the plan is behind this.

Evil people behind this, and well aware of these.

PROOF: Bill Gates Putting Implantable Chips In Vaccines (bitchute.com)

Former Pfizer VP: ‘Your government is lying to you in a way that could lead to your death.’

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‘Look out the window, and think, “why is my government lying to me about something so fundamental?” Because, I think the answer is, they are going to kill you using this method. They’re going to kill you and your family.’
Wed Apr 7, 2021 - 8:47 am EST

Covid - 19 Vaccines Adverse Reactions Update EU , US , UK data

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EU - 17,503   Dead           1,700,503.    Injuries                          July   3      2021

US. - 10,991   Dead           551,172       Injuries                           July  9.     2021

UK - 1,440    Dead            309,272       Reported  Injured        June 30     2021 

 EU-From the total of injuries recorded, half of them (837,588 ) are serious injuries.

USA- an  additional  997 deaths among unborn children,

 



U.S. Grant Gave Money to the Wuhan Lab to Enhance Coronaviruses, the Decision Wasn't Even Scrutinized

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The United States gave a grant of $600,000 to the Wuhan Institute of Virology, and the decision wasn’t even scrutinized by the agency Dr. Anthony Fauci heads up. This per a new report from The Daily Caller which lays out in detail exactly how the transfer happened and the lack of oversight involved.

SARS-CoV-2 Prion-Like Domains in Spike Proteins Enable Higher Affinity to ACE2

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Currently, the world is struggling with the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Prion-like domains are critical for virulence and the development of therapeutic targets; however, the prion- like domains in the SARS-CoV-2 proteome have not been analyzed. In this in silico study, using the PLAAC algorithm, we identified the presence of prion-like domains in the SARS-CoV-2 spike protein. Compared with other viruses, a striking difference was observed in the distribution of prion-like domains in the spike protein, since SARS-CoV-2 was the only coronavirus with a prion- like domain found in the receptor-binding domain of the S1 region of the spike protein. The presence and unique distribution of prion-like domains in the SARS-CoV-2 receptor-binding domains of the spike protein is particularly interesting, since although the SARS-CoV-2 and SARS-CoV S proteins share the same host cell receptor, angiotensin-converting enzyme 2 (ACE2), SARS-CoV-2 demonstrates a 10- to 20-fold higher affinity for ACE2. Finally, we identified prion-like domains in the α1 helix of the ACE2 receptor that interact with the viral receptor-binding domain of SARS-CoV-2. Taken together, the present findings indicate that the identified PrDs in the SARS-CoV-2 receptor-binding domain (RBD) and ACE2 region that interact with RBD have important functional roles in viral adhesion and entry.

COVID-19: Pandemic? Or Cult?

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For the overwhelming majority of people, COVID-19 is a religion. On faith, they blindly accept that SARS-CoV-2 is the virus that causes COVID-19. On faith they believe that COVID-19 PCR, antigen and antibody tests are accurate. On faith they believe that vaccines using an experimental mRNA technology never before used on humans, developed in less than a year instead of the normal 5-10 years to evaluate the long-term effects on people’s health, are safe and effective.

On faith they believe that draconian measures, like mask mandates and global lockdowns that have destroyed lives, economies, and trampled centuries of cherished civil liberties will protect them. On faith they believe that doctors, scientists, politicians, public health bureaucrats, and the mainstream media are telling them the truth about COVID-19.

Having faith in yourself is one thing. But placing your faith in some institution like the World Health Organization or in some person because they’re a doctor, scientist, president, king, queen, prime minster, governor, mayor, or a celebrity is giving away your power.

6-month neurological and psychiatric outcomes in 236379 survivors of COVID-19: a retrospective cohort study using electronic health records

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Among 236 379 patients diagnosed with COVID-19, the estimated incidence of a neurological or psychiatric diagnosis in the following 6 months was 33·62% (95% CI 33·17–34·07), with 12·84% (12·36–13·33) receiving their first such diagnosis. For patients who had been admitted to an ITU, the estimated incidence of a diagnosis was 46·42% (44·78–48·09) and for a first diagnosis was 25·79% (23·50–28·25). Regarding individual diagnoses of the study outcomes, the whole COVID-19 cohort had estimated incidences of 0·56% (0·50–0·63) for intracranial haemorrhage, 2·10% (1·97–2·23) for ischaemic stroke, 0·11% (0·08–0·14) for parkinsonism, 0·67% (0·59–0·75) for dementia, 17·39% (17·04–17·74) for anxiety disorder, and 1·40% (1·30–1·51) for psychotic disorder, among others. In the group with ITU admission, estimated incidences were 2·66% (2·24–3·16) for intracranial haemorrhage, 6·92% (6·17–7·76) for ischaemic stroke, 0·26% (0·15–0·45) for parkinsonism, 1·74% (1·31–2·30) for dementia, 19·15% (17·90–20·48) for anxiety disorder, and 2·77% (2·31–3·33) for psychotic disorder. Most diagnostic categories were more common in patients who had COVID-19 than in those who had influenza (hazard ratio [HR] 1·44, 95% CI 1·40–1·47, for any diagnosis; 1·78, 1·68–1·89, for any first diagnosis) and those who had other respiratory tract infections (1·16, 1·14–1·17, for any diagnosis; 1·32, 1·27–1·36, for any first diagnosis). As with incidences, HRs were higher in patients who had more severe COVID-19 (eg, those admitted to ITU compared with those who were not: 1·58, 1·50–1·67, for any diagnosis; 2·87, 2·45–3·35, for any first diagnosis). Results were robust to various sensitivity analyses and benchmarking against the four additional index health events.

Interpretation

Our study provides evidence for substantial neurological and psychiatric morbidity in the 6 months after COVID-19 infection. Risks were greatest in, but not limited to, patients who had severe COVID-19. This information could help in service planning and identification of research priorities. Complementary study designs, including prospective cohorts, are needed to corroborate and explain these findings.
Maxime Taquet, John R Geddes, Masud Husain, Sierra Luciano, Paul J Harrison

CDC corona vaccine death report: 31,079 adverse events, including 1,524 deaths, 5,507 serious injuries and 390 reports of Bell’s Palsy

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Between Dec. 14, 2020, and Mar. 5, 2021, 31,079 reports of adverse events were submitted to VAERS, including 1,524 deaths, 5,507 serious injuries and 390 reports of Bell’s Palsy.

Shocking Study Reveals mRNA COVID-19 Vaccines May Progressively Degenerate Your Brain From Prion Disease

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Shocking Study Reveals mRNA COVID-19 Vaccines May Progressively Degenerate Your Brain From Prion Disease

DR PETER MCCULLOUGH SAYS HIGHLY EFFECTIVE EARLY TREATMENT FOR COVID HAS BEEN CENSORED

If you find a treatment or treatments that work for Covid 19, they might also work on other infectious/viral diseases, which would make not only covid 19 but also most other vaccines obsolete. This scenario is a nightmare for the medical industry and must be stopped at every cost.

No more lockdowns: UK will treat Covid like seasonal flu, says Chris Whitty

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Lockdowns will likely become a thing of the past once England emerges from restrictions in June, Professor Chris Whitty has said, as he suggested Britain will treat coronavirus like the flu in the future.

England’s chief medical officer said the UK would have to learn to live with the virus, noting that up to 25,000 people can die in a bad flu year without the figure hitting the headlines.

Women say they are having heavier and more painful PERIODS since getting their COVID-19 vaccines - as several claim it has also messed up their monthly cycle

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  • Dr. Kate Clancy, a University of Illinois associate professor, said that she'd heard people had experienced changes in their menstruation since getting vaccinated
  • Her tweet prompted other women to share changes to their own periods
  • Several reported that they were bleeding more heavily and for longer than they had before getting the vaccine 

8 Weeks To Reverse Covid-19 Laws

Could mRNA Vaccines Permanently Alter DNA? Recent Science Suggests They Might.

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Research on SARS-CoV-2 RNA by scientists at Harvard and MIT has implications for how mRNA vaccines could permanently alter genomic DNA, according to Doug Corrigan, Ph.D., a biochemist-molecular biologist who says more research is needed.

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