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Abstract
Antimicrobial-resistant (AMR) infections currently claim at least 50,000 lives each year
across Europe and the US alone, with many hundreds of thousands more dying in other areas
of the world. In 15 European countries, more than 10% of bloodstream Staphylococcus
aureus infections are caused by methicillin-resistant strains (MRSA), with several of these
countries seeing resistance rates closer to 50%.1Moreover, while the number of antibiotic-
resistant infections is on the rise, the number of new antibiotics is declining.1,2It is therefore
imperative that new, novel treatments of AMR’s are sought, and this is the premise of this
research – using natural substances to eradicate MRSA, that do not create further resistance.
Chlorine dioxide used in vitro, has been our main focus of this research, as it was the most
effective, compared to other natural substances tested.
Keywords:antimicrobial-resistant, methicillin-resistant strains, staphylococcus aureu,
toxic shock syndrome, erythromycin, chlorine dioxide