Treatment Protocol against Covid 19 from www.ippocrateorg.org
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The indications which are presented below are the guidelines which physicians working at IppocrateOrg Call Centre are currently referring to when treating Covid-19 patients.
We want to emphasise that drugs and supplements and their dosage are to be considered as a mere indication. The treating physician must determine and prescribe the appropriate therapy for each patient.
So NEVER without a doctor!
In order to get the best ‘at home therapy’ for outpatients, basic guidelines proposed (updated to 27th March 2021) by IppocrateOrg, consider the progression of the disease in 3 stages, as they are well known from the majority of clinicians:
| STAGE | PATHOPHYSIOLOGY | CLINIC | |
|---|---|---|---|
| STAGE 1 (Early Infection) |
Virus replication | Flu-like symptoms (fever, joint and muscle pain, headache, weakness..) | |
| STAGE 2 (Pulmonary Phase) |
Lung complication | Cough, dyspnoea, polypnoea | |
| STAGE 2A W/out hypoxia |
STAGE 2B With hypoxia |
||
| STAGE 3 (Hyperinflammation Phase) |
Cytokine storm or hypercytokinemia | SARS, vasculitis, microembolism, microthrombosis, multi-organ failure | |
We define STAGE ZERO as a test-positive patient without symptoms.
We suggest application of STAGE ZERO therapy to all close contacts.
The recovery from Covid is often very long. We propose the following treatments to shorten it.
Early treatment is the winning strategy
STAGE Zero
(Asymptomatic and test-positive patient)
| DRUG | DOSAGE | CONTRAINDICATIONS |
|---|---|---|
| Vitamin D3 | 50.000 IU/day for 6 days (if not in prophylaxis) 10.000 IU./day for 6 days (if in prophylaxis) And then 4.000 IU/day While eating a greasy meal (for example at lunch Children: 200 IU/Kg/day (until negative test) |
Severe Chronic Kidney Insufficiency (CKD) |
| Vitamin C | From 1 g/day, in consideration of formulation | Severe CKD, deficit G6PD |
| Zinc picolinate | 30-50 mg/day | |
| Esperidine | 100 mg/day | |
| Quercetin | Up to 250 mg x 2/day | |
| Lactoferrin | Up to 200 mg x 2/day | |
| Bromexine | 8 mg x 3/day | |
| Pelargonium S. | > 12 y-o: 20 mg x 3/day for 7 days 6-12 y-o: 13 mg x 3/day for 7 days |
Hemorrhagic diathesis F.E in patient in treatment with blood thinners |
| Suffumigation | 3 times/day | |
| Hydrossitirosol and α-cyclodestrine | 2-3 puffs x 3-4/day in the throat |
Other active ingredients known for their antiviral action
| Vitamin A | Up to 30.000 IU/day | Pregnancy |
| Resveratrol | Up to 1000 mg/day |
The proper combination of medications from the list will be prescribed by the physician, according to the patient’s needs and characteristics.
Our indication – in any case – is to prescribe:
✔ Vitamin D
✔ Zinc
✔ Vitamin C
which we recommend to be prescribed even in severe stages of the disease.
Hence if the patient is treated in stage 1 or 2, do not forget about prescribing these supplements in conjunction with the other drugs.
⬇️
STAGE 1
(flu-like symptoms)
| DRUG | DOSAGE | CONTRAINDICATIONS |
|---|---|---|
| ASA | Up to 100 mg/day till asymptomatic | |
| Ivermectine | 0,2 mg/Kg of Body weight, maximum PC 18 mg 2ª dose after 48 hours 3ª dose (eventually) 48 hours after |
|
| Hydroxychloroquine (HCQ) | 200 mg x 2/day for 7 days | Arrhythmias, Retinopathy Def. G6PDH |
| Azithromycin or Doxycycline |
500 mg/day for 3 days, stop 2 days, then repeat | LQTS |
| 100 mg x 2/day for 7 days | ||
| Colchicine | 0.5 mg x 2/day for 14 days | Cardiac Insuff., CKD do not use with Clarithromicin |
⬇️
STAGE 2A
(lung complication without hypoxia)
| DRUG | DOSAGE | CONTRAINDICATIONS |
|---|---|---|
| Montelukast | 10 mg 2 hours after dinner for 14 days | |
| Amoxi/Clavulanic acid or Other antibiotics |
875 mg+125 mg x 3/day for 8-10 days | |
| In association with Azithromycin in case of superinfection | ||
| Acetylcysteine | 600 mg up to x 3/day fro 7 days | |
| Levodropropizine | 60 mg as needed, up to x 3/day | |
| Enoxaparin | 4.000 IU x 1-2/day for 10 days if weight < 70 Kg 6.000 IU x 1-2/day for 10 days if weight 70-100 Kg |
Hemorrhagic diathesis Thrombocytopenia |
N.B.: Practitioner will evaluate if patient will need corticosteroid on therapy as in stage 2B.
It is advisable to do thoracic ecography and/or ct scan
⬇️
STAGE 2B
(lung complication with hypoxia)
| DRUG | DOSAGE | CONTRAINDICATIONS |
|---|---|---|
| O2-therapy | 1-6 L/min if SpO2 < 92% in AA | |
| Enoxaparin | 100 IU/Kg/12 hours | |
| Dexamethasone ⚠️ | 6 mg/morning OR 3 mg x 2/day | ● do not associate but use alternatively ● associate gastroprot. |
| Betamethasone ⚠️ | 8 mg/morning OR 4 mg x 2/day | |
| Methylprednisolone ⚠️ | 32 mg/morning OR 16 mg x 2/day | |
| Prednisone ⚠️ | 40 mg/morning OR 20 mg x 2/day | |
| Deflazacort ⚠️ | 30 mg x 2/day | |
| Antibiotics | According to practitioner’s judgment |
Corticosteroids: NEVER AT THE BEGINNING, but only at the end of the viral stage!!
● for 6-7 days then diminish
● better one morning dose
● 2 doses if patient is suffering (always Deflazacort, for its fast action)
Contraindications: Hypertension, Hyperglycaemia, …
In case Oxygen > 6 L/min
or
SpO2 persistently < 92%
⬇️
HOSPITALISATION IS MANDATORY
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